WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Osteoclast differentiation       ID:04380
C=128; O=29; E=1.76; R=16.48; rawP=6.84e-27; adjP=7.46e-25
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131042 NA LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 10288 ENSG00000131042
2  ENSG00000072694 NA FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2213 ENSG00000072694
3  ENSG00000100365 NA NCF4 neutrophil cytosolic factor 4, 40kDa 4689 ENSG00000100365
4  ENSG00000186818 NA LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 11006 ENSG00000186818
5  ENSG00000095970 NA TREM2 triggering receptor expressed on myeloid cells 2 54209 ENSG00000095970
6  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
7  ENSG00000010671 NA BTK Bruton agammaglobulinemia tyrosine kinase 695 ENSG00000010671
8  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
9  ENSG00000104972 NA LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 10859 ENSG00000104972
10  ENSG00000043462 NA LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 3937 ENSG00000043462
11  ENSG00000170909 NA OSCAR osteoclast associated, immunoglobulin-like receptor 126014 ENSG00000170909
12  ENSG00000116701 NA NCF2 neutrophil cytosolic factor 2 4688 ENSG00000116701
13  ENSG00000203747 NA FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2214 ENSG00000203747
14  ENSG00000051523 NA CYBA cytochrome b-245, alpha polypeptide 1535 ENSG00000051523
15  ENSG00000141506 NA PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 23533 ENSG00000141506
16  ENSG00000104974 NA LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 11024 ENSG00000104974
17  ENSG00000158517 NA NCF1 neutrophil cytosolic factor 1 653361 ENSG00000158517
18  ENSG00000143226 NA FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2212 ENSG00000143226
19  ENSG00000105609 NA LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 10990 ENSG00000105609
20  ENSG00000156711 NA MAPK13 mitogen-activated protein kinase 13 5603 ENSG00000156711
21  ENSG00000011600 NA TYROBP TYRO protein tyrosine kinase binding protein 7305 ENSG00000011600
22  ENSG00000244482 NA LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 79168 ENSG00000244482
23  ENSG00000239998 NA LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 11027 ENSG00000239998
24  ENSG00000204577 NA LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 11025 ENSG00000204577
25  ENSG00000066336 NA SPI1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 6688 ENSG00000066336
26  ENSG00000165025 NA SYK spleen tyrosine kinase 6850 ENSG00000165025
27  ENSG00000102575 NA ACP5 acid phosphatase 5, tartrate resistant 54 ENSG00000102575
28  ENSG00000165168 NA CYBB cytochrome b-245, beta polypeptide 1536 ENSG00000165168
29  ENSG00000182578 NA CSF1R colony stimulating factor 1 receptor 1436 ENSG00000182578


Database:KEGG pathway       Name:Chemokine signaling pathway       ID:04062
C=189; O=32; E=2.60; R=12.31; rawP=2.58e-25; adjP=1.41e-23
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000167236 NA CCL23 chemokine (C-C motif) ligand 23 6368 ENSG00000167236
2  ENSG00000172724 NA CCL19 chemokine (C-C motif) ligand 19 6363 ENSG00000172724
3  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
4  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
5  ENSG00000254087 NA LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 4067 ENSG00000254087
6  ENSG00000134516 NA DOCK2 dedicator of cytokinesis 2 1794 ENSG00000134516
7  ENSG00000141968 NA VAV1 vav 1 guanine nucleotide exchange factor 7409 ENSG00000141968
8  ENSG00000128340 NA RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5880 ENSG00000128340
9  ENSG00000161921 NA CXCL16 chemokine (C-X-C motif) ligand 16 58191 ENSG00000161921
10  ENSG00000163823 NA CCR1 chemokine (C-C motif) receptor 1 1230 ENSG00000163823
11  ENSG00000141506 NA PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 23533 ENSG00000141506
12  ENSG00000158517 NA NCF1 neutrophil cytosolic factor 1 653361 ENSG00000158517
13  ENSG00000129277 NA CCL4 chemokine (C-C motif) ligand 4 6351 ENSG00000129277
14  ENSG00000102962 NA CCL22 chemokine (C-C motif) ligand 22 6367 ENSG00000102962
15  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
16  ENSG00000137841 NA PLCB2 phospholipase C, beta 2 5330 ENSG00000137841
17  ENSG00000173578 NA XCR1 chemokine (C motif) receptor 1 2829 ENSG00000173578
18  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263
19  ENSG00000134215 NA VAV3 vav 3 guanine nucleotide exchange factor 10451 ENSG00000134215
20  ENSG00000124126 NA PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 57580 ENSG00000124126
21  ENSG00000121807 NA CCR2 chemokine (C-C motif) receptor 2 729230 ENSG00000121807
22  ENSG00000168243 NA GNG4 guanine nucleotide binding protein (G protein), gamma 4 2786 ENSG00000168243
23  ENSG00000101336 NA HCK hemopoietic cell kinase 3055 ENSG00000101336
24  ENSG00000000938 NA FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 2268 ENSG00000000938
25  ENSG00000015285 NA WAS Wiskott-Aldrich syndrome 7454 ENSG00000015285
26  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
27  ENSG00000166501 NA PRKCB protein kinase C, beta 5579 ENSG00000166501
28  ENSG00000181374 NA CCL13 chemokine (C-C motif) ligand 13 6357 ENSG00000181374
29  ENSG00000120899 NA PTK2B PTK2B protein tyrosine kinase 2 beta 2185 ENSG00000120899
30  ENSG00000141480 NA ARRB2 arrestin, beta 2 409 ENSG00000141480
31  ENSG00000006074 NA CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 6362 ENSG00000006074
32  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:KEGG pathway       Name:Staphylococcus aureus infection       ID:05150
C=55; O=19; E=0.76; R=25.12; rawP=5.65e-22; adjP=2.05e-20
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000224389 NA C4B complement component 4B (Chido blood group) 721 ENSG00000224389
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000169403 NA PTAFR platelet-activating factor receptor 5724 ENSG00000169403
4  ENSG00000072694 NA FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2213 ENSG00000072694
5  ENSG00000110876 NA SELPLG selectin P ligand 6404 ENSG00000110876
6  ENSG00000244731 NA C4A complement component 4A (Rodgers blood group) 720 ENSG00000244731
7  ENSG00000169896 NA ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3684 ENSG00000169896
8  ENSG00000205403 NA CFI complement factor I 3426 ENSG00000205403
9  ENSG00000136634 NA IL10 interleukin 10 3586 ENSG00000136634
10  ENSG00000203747 NA FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2214 ENSG00000203747
11  ENSG00000160255 NA ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3689 ENSG00000160255
12  ENSG00000173369 NA C1QB complement component 1, q subcomponent, B chain 713 ENSG00000173369
13  ENSG00000173372 NA C1QA complement component 1, q subcomponent, A chain 712 ENSG00000173372
14  ENSG00000159189 NA C1QC complement component 1, q subcomponent, C chain 714 ENSG00000159189
15  ENSG00000143226 NA FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2212 ENSG00000143226
16  ENSG00000187474 NA FPR3 formyl peptide receptor 3 2359 ENSG00000187474
17  ENSG00000166278 NA C2 complement component 2 717 ENSG00000166278
18  ENSG00000241106 NA HLA-DOB major histocompatibility complex, class II, DO beta 3112 ENSG00000241106
19  ENSG00000171860 NA C3AR1 complement component 3a receptor 1 719 ENSG00000171860


Database:KEGG pathway       Name:Cytokine-cytokine receptor interaction       ID:04060
C=265; O=33; E=3.64; R=9.06; rawP=1.05e-21; adjP=2.29e-20
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000161955 NA TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 8741 ENSG00000161955
2  ENSG00000167236 NA CCL23 chemokine (C-C motif) ligand 23 6368 ENSG00000167236
3  ENSG00000172724 NA CCL19 chemokine (C-C motif) ligand 19 6363 ENSG00000172724
4  ENSG00000198223 NA CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1438 ENSG00000198223
5  ENSG00000227507 NA LTB lymphotoxin beta (TNF superfamily, member 3) 4050 ENSG00000227507
6  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
7  ENSG00000102524 NA TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 10673 ENSG00000102524
8  ENSG00000121807 NA CCR2 chemokine (C-C motif) receptor 2 729230 ENSG00000121807
9  ENSG00000150782 NA IL18 interleukin 18 (interferon-gamma-inducing factor) 3606 ENSG00000150782
10  ENSG00000096996 NA IL12RB1 interleukin 12 receptor, beta 1 3594 ENSG00000096996
11  ENSG00000136634 NA IL10 interleukin 10 3586 ENSG00000136634
12  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
13  ENSG00000101017 NA CD40 CD40 molecule, TNF receptor superfamily member 5 958 ENSG00000101017
14  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
15  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
16  ENSG00000106952 NA TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 944 ENSG00000106952
17  ENSG00000110944 NA IL23A interleukin 23, alpha subunit p19 51561 ENSG00000110944
18  ENSG00000110324 NA IL10RA interleukin 10 receptor, alpha 3587 ENSG00000110324
19  ENSG00000100368 NA CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 1439 ENSG00000100368
20  ENSG00000028137 NA TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 7133 ENSG00000028137
21  ENSG00000161921 NA CXCL16 chemokine (C-X-C motif) ligand 16 58191 ENSG00000161921
22  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
23  ENSG00000163823 NA CCR1 chemokine (C-C motif) receptor 1 1230 ENSG00000163823
24  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
25  ENSG00000129277 NA CCL4 chemokine (C-C motif) ligand 4 6351 ENSG00000129277
26  ENSG00000102962 NA CCL22 chemokine (C-C motif) ligand 22 6367 ENSG00000102962
27  ENSG00000181374 NA CCL13 chemokine (C-C motif) ligand 13 6357 ENSG00000181374
28  ENSG00000134460 NA IL2RA interleukin 2 receptor, alpha 3559 ENSG00000134460
29  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
30  ENSG00000006074 NA CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 6362 ENSG00000006074
31  ENSG00000173578 NA XCR1 chemokine (C motif) receptor 1 2829 ENSG00000173578
32  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791
33  ENSG00000182578 NA CSF1R colony stimulating factor 1 receptor 1436 ENSG00000182578


Database:KEGG pathway       Name:Hematopoietic cell lineage       ID:04640
C=88; O=22; E=1.21; R=18.18; rawP=9.77e-22; adjP=2.29e-20
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000010610 NA CD4 CD4 molecule 920 ENSG00000010610
2  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
3  ENSG00000115232 NA ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 3676 ENSG00000115232
4  ENSG00000198223 NA CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 1438 ENSG00000198223
5  ENSG00000169896 NA ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3684 ENSG00000169896
6  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
7  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
8  ENSG00000170458 NA CD14 CD14 molecule 929 ENSG00000170458
9  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
10  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
11  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
12  ENSG00000166825 NA ANPEP alanyl (membrane) aminopeptidase 290 ENSG00000166825
13  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
14  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
15  ENSG00000104894 NA CD37 CD37 molecule 951 ENSG00000104894
16  ENSG00000104921 NA FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2208 ENSG00000104921
17  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
18  ENSG00000203710 NA CR1 complement component (3b/4b) receptor 1 (Knops blood group) 1378 ENSG00000203710
19  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
20  ENSG00000134460 NA IL2RA interleukin 2 receptor, alpha 3559 ENSG00000134460
21  ENSG00000105383 NA CD33 CD33 molecule 945 ENSG00000105383
22  ENSG00000182578 NA CSF1R colony stimulating factor 1 receptor 1436 ENSG00000182578


Database:KEGG pathway       Name:Natural killer cell mediated cytotoxicity       ID:04650
C=136; O=24; E=1.87; R=12.83; rawP=9.38e-20; adjP=1.70e-18
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
2  ENSG00000134215 NA VAV3 vav 3 guanine nucleotide exchange factor 10451 ENSG00000134215
3  ENSG00000126264 NA HCST hematopoietic cell signal transducer 10870 ENSG00000126264
4  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
5  ENSG00000198574 NA SH2D1B SH2 domain containing 1B 117157 ENSG00000198574
6  ENSG00000158869 NA FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2207 ENSG00000158869
7  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
8  ENSG00000111679 NA PTPN6 protein tyrosine phosphatase, non-receptor type 6 5777 ENSG00000111679
9  ENSG00000204516 NA MICB MHC class I polypeptide-related sequence B 4277 ENSG00000204516
10  ENSG00000043462 NA LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 3937 ENSG00000043462
11  ENSG00000100453 NA GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 3002 ENSG00000100453
12  ENSG00000203747 NA FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2214 ENSG00000203747
13  ENSG00000141968 NA VAV1 vav 1 guanine nucleotide exchange factor 7409 ENSG00000141968
14  ENSG00000160255 NA ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3689 ENSG00000160255
15  ENSG00000128340 NA RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5880 ENSG00000128340
16  ENSG00000183918 NA SH2D1A SH2 domain containing 1A 4068 ENSG00000183918
17  ENSG00000141506 NA PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 23533 ENSG00000141506
18  ENSG00000166501 NA PRKCB protein kinase C, beta 5579 ENSG00000166501
19  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
20  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
21  ENSG00000120899 NA PTK2B PTK2B protein tyrosine kinase 2 beta 2185 ENSG00000120899
22  ENSG00000011600 NA TYROBP TYRO protein tyrosine kinase binding protein 7305 ENSG00000011600
23  ENSG00000180644 NA PRF1 perforin 1 (pore forming protein) 5551 ENSG00000180644
24  ENSG00000165025 NA SYK spleen tyrosine kinase 6850 ENSG00000165025


Database:KEGG pathway       Name:T cell receptor signaling pathway       ID:04660
C=108; O=22; E=1.49; R=14.81; rawP=1.22e-19; adjP=1.90e-18
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134215 NA VAV3 vav 3 guanine nucleotide exchange factor 10451 ENSG00000134215
2  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
3  ENSG00000010610 NA CD4 CD4 molecule 920 ENSG00000010610
4  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
5  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
6  ENSG00000111679 NA PTPN6 protein tyrosine phosphatase, non-receptor type 6 5777 ENSG00000111679
7  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
8  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
9  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
10  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
11  ENSG00000136634 NA IL10 interleukin 10 3586 ENSG00000136634
12  ENSG00000043462 NA LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 3937 ENSG00000043462
13  ENSG00000141968 NA VAV1 vav 1 guanine nucleotide exchange factor 7409 ENSG00000141968
14  ENSG00000081237 NA PTPRC protein tyrosine phosphatase, receptor type, C 5788 ENSG00000081237
15  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
16  ENSG00000141506 NA PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 23533 ENSG00000141506
17  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
18  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
19  ENSG00000156711 NA MAPK13 mitogen-activated protein kinase 13 5603 ENSG00000156711
20  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
21  ENSG00000178562 NA CD28 CD28 molecule 940 ENSG00000178562
22  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263


Database:KEGG pathway       Name:Leukocyte transendothelial migration       ID:04670
C=116; O=20; E=1.60; R=12.54; rawP=1.76e-16; adjP=2.40e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
2  ENSG00000134215 NA VAV3 vav 3 guanine nucleotide exchange factor 10451 ENSG00000134215
3  ENSG00000100365 NA NCF4 neutrophil cytosolic factor 4, 40kDa 4689 ENSG00000100365
4  ENSG00000115232 NA ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 3676 ENSG00000115232
5  ENSG00000169896 NA ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3684 ENSG00000169896
6  ENSG00000136653 NA RASSF5 Ras association (RalGDS/AF-6) domain family member 5 83593 ENSG00000136653
7  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
8  ENSG00000116701 NA NCF2 neutrophil cytosolic factor 2 4688 ENSG00000116701
9  ENSG00000141968 NA VAV1 vav 1 guanine nucleotide exchange factor 7409 ENSG00000141968
10  ENSG00000160255 NA ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3689 ENSG00000160255
11  ENSG00000128340 NA RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5880 ENSG00000128340
12  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
13  ENSG00000051523 NA CYBA cytochrome b-245, alpha polypeptide 1535 ENSG00000051523
14  ENSG00000141506 NA PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 23533 ENSG00000141506
15  ENSG00000166501 NA PRKCB protein kinase C, beta 5579 ENSG00000166501
16  ENSG00000158517 NA NCF1 neutrophil cytosolic factor 1 653361 ENSG00000158517
17  ENSG00000120899 NA PTK2B PTK2B protein tyrosine kinase 2 beta 2185 ENSG00000120899
18  ENSG00000156711 NA MAPK13 mitogen-activated protein kinase 13 5603 ENSG00000156711
19  ENSG00000165168 NA CYBB cytochrome b-245, beta polypeptide 1536 ENSG00000165168
20  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263


Database:KEGG pathway       Name:B cell receptor signaling pathway       ID:04662
C=75; O=17; E=1.03; R=16.48; rawP=2.54e-16; adjP=3.08e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000141968 NA VAV1 vav 1 guanine nucleotide exchange factor 7409 ENSG00000141968
2  ENSG00000105369 NA CD79A CD79a molecule, immunoglobulin-associated alpha 973 ENSG00000105369
3  ENSG00000072694 NA FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2213 ENSG00000072694
4  ENSG00000134215 NA VAV3 vav 3 guanine nucleotide exchange factor 10451 ENSG00000134215
5  ENSG00000128340 NA RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5880 ENSG00000128340
6  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
7  ENSG00000166501 NA PRKCB protein kinase C, beta 5579 ENSG00000166501
8  ENSG00000141506 NA PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 23533 ENSG00000141506
9  ENSG00000155629 NA PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 118788 ENSG00000155629
10  ENSG00000111679 NA PTPN6 protein tyrosine phosphatase, non-receptor type 6 5777 ENSG00000111679
11  ENSG00000168918 NA INPP5D inositol polyphosphate-5-phosphatase, 145kDa 3635 ENSG00000168918
12  ENSG00000010671 NA BTK Bruton agammaglobulinemia tyrosine kinase 695 ENSG00000010671
13  ENSG00000070190 NA DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 27071 ENSG00000070190
14  ENSG00000137101 NA CD72 CD72 molecule 971 ENSG00000137101
15  ENSG00000254087 NA LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 4067 ENSG00000254087
16  ENSG00000204577 NA LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 11025 ENSG00000204577
17  ENSG00000165025 NA SYK spleen tyrosine kinase 6850 ENSG00000165025


Database:KEGG pathway       Name:Phagosome       ID:04145
C=153; O=22; E=2.10; R=10.46; rawP=2.97e-16; adjP=3.24e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000072694 NA FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2213 ENSG00000072694
2  ENSG00000172243 NA CLEC7A C-type lectin domain family 7, member A 64581 ENSG00000172243
3  ENSG00000100365 NA NCF4 neutrophil cytosolic factor 4, 40kDa 4689 ENSG00000100365
4  ENSG00000120586 NA MRC1 mannose receptor, C type 1 4360 ENSG00000120586
5  ENSG00000169896 NA ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3684 ENSG00000169896
6  ENSG00000090659 NA CD209 CD209 molecule 30835 ENSG00000090659
7  ENSG00000038945 NA MSR1 macrophage scavenger receptor 1 4481 ENSG00000038945
8  ENSG00000170458 NA CD14 CD14 molecule 929 ENSG00000170458
9  ENSG00000174130 NA TLR6 toll-like receptor 6 10333 ENSG00000174130
10  ENSG00000116701 NA NCF2 neutrophil cytosolic factor 2 4688 ENSG00000116701
11  ENSG00000203747 NA FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2214 ENSG00000203747
12  ENSG00000019169 NA MARCO macrophage receptor with collagenous structure 8685 ENSG00000019169
13  ENSG00000160255 NA ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3689 ENSG00000160255
14  ENSG00000158270 NA COLEC12 collectin sub-family member 12 81035 ENSG00000158270
15  ENSG00000163131 NA CTSS cathepsin S 1520 ENSG00000163131
16  ENSG00000051523 NA CYBA cytochrome b-245, alpha polypeptide 1535 ENSG00000051523
17  ENSG00000158517 NA NCF1 neutrophil cytosolic factor 1 653361 ENSG00000158517
18  ENSG00000143226 NA FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2212 ENSG00000143226
19  ENSG00000102879 NA CORO1A coronin, actin binding protein, 1A 11151 ENSG00000102879
20  ENSG00000241106 NA HLA-DOB major histocompatibility complex, class II, DO beta 3112 ENSG00000241106
21  ENSG00000065665 NA SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 55176 ENSG00000065665
22  ENSG00000165168 NA CYBB cytochrome b-245, beta polypeptide 1536 ENSG00000165168




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).